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bionic [2023/02/23 16:08]
trynke
bionic [2025/02/05 14:49] (current)
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 The first questionnaire (DEPQ) comprised of the [[Depression (LIDAS)|Lifetime Depression Assessment Self-Report]] (LIDAS). The second questionnaire (DEAQ) was performed in collaboration with the [[https://​umcgresearch.org/​en-GB/​w/​university-center-of-psychiatry-ucp-|University Center of Psychiatry]] at the UMCG in Groningen and contained both the LIDAS and several additional questions (e.g. on lifetime anxiety disorders).\\ ​ The first questionnaire (DEPQ) comprised of the [[Depression (LIDAS)|Lifetime Depression Assessment Self-Report]] (LIDAS). The second questionnaire (DEAQ) was performed in collaboration with the [[https://​umcgresearch.org/​en-GB/​w/​university-center-of-psychiatry-ucp-|University Center of Psychiatry]] at the UMCG in Groningen and contained both the LIDAS and several additional questions (e.g. on lifetime anxiety disorders).\\ ​
 Note that **recent/​ongoing** depression & anxiety of Lifelines participants were assessed in general assessments [[1A]], [[2A]] and [[3A]] using the [[MINI Neuropsychiatric Interview|MINI]]. Note that **recent/​ongoing** depression & anxiety of Lifelines participants were assessed in general assessments [[1A]], [[2A]] and [[3A]] using the [[MINI Neuropsychiatric Interview|MINI]].
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 +The Bionic variables are available for use for all researchers and can be requested through the catalogue. Questions to the contact person of the additional questionnaire can be asked through Lifelines (e-mail data@lifelines.nl).
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 +When the LIDAS items of DEPQ/DEAQ have been used in your research, you will have to include the following references:
 +  * [[https://​doi.org/​10.1017/​S0033291716002312|Bot et al., Validity of LIDAS (LIfetime Depression Assessment Self-report):​ a self-report online assessment of lifetime major depressive disorder. Psychol Med. 2017 Jan;​47(2):​279-289))]] ​
 +  * [[https://​doi.org/​10.1017/​S0033291720000100|Fedko et al. Measurement and genetic architecture of lifetime depression in the Netherlands as assessed by LIDAS (Lifetime Depression Assessment Self-report). Psychol Med. 2020 Jan;51(8): 1-10]]
 +
 +When the DEAQ data has been used in your research, you will have to include the following reference:
 +  * [[https://​doi.org/​10.1016/​j.jad.2022.03.064|van Loo et al., The structure of the symptoms of major depression: Factor analysis of a lifetime worst episode of depressive symptoms in a large general population sample. J Affect Disord 2022; 307: 115-124]] ​
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 +
  
 ===== Subcohort ===== ===== Subcohort =====
-  * For DEPQ (2016), the [[Depression (LIDAS)|LIDAS]] was sent to all adult participants with a known e-mail address within the [[GWAS]] subcohort (n=~10.000). ~5500 participants (50%) filled in the questionnaire. ​((Bot et al., Validity of LIDAS (LIfetime Depression Assessment Self-report):​ a self-report online assessment of lifetime major depressive disorder. Psychol Med. 2017 Jan;​47(2):​279-289)) ((Fedko et al., Measurement and genetic architecture of lifetime depression in the Netherlands as assessed by LIDAS (Lifetime Depression Assessment Self-report). Psychol Med. 2022 Feb;​51(8):​1-10))\\ +  * For DEPQ (2016), the [[Depression (LIDAS)|LIDAS]] was sent to all adult participants with a known e-mail address within the [[GWAS]] subcohort (n=~10.000). ~5500 participants (50%) filled in the questionnaire.\\ 
-  * For  DEAQ (2018), the [[Depression (LIDAS)|LIDAS]] plus additional questions (mostly regarding lifetime anxiety) was sent to all adult participants with a known e-mail address in the entire [[cohort]] (n=133.000). ~43.500 participants (36%) filled in the questionnaire. ​ ((van Loo et al., The structure of the symptoms of major depression: Factor analysis of a lifetime worst episode of depressive symptoms in a large general population sample. J Affect Disord 307: 115-124))+  * For  DEAQ (2018), the [[Depression (LIDAS)|LIDAS]] plus additional questions (mostly regarding lifetime anxiety) was sent to all adult participants with a known e-mail address in the entire [[cohort]] (n=133.000). ~43.500 participants (36%) filled in the questionnaire.
  
 ===== Variables ===== ===== Variables =====
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 DEPQ consisted of variables in the following subsections:​ DEPQ consisted of variables in the following subsections:​
  
-  * [[Depression (LIDAS)]] ​(only depression-related questions)+  * [[Depression (LIDAS)]] -> note that for DEPQ, the original LIDAS was used
   * [[Smoking & tobacco use]]    * [[Smoking & tobacco use]] 
   * [[Education | Education]]   * [[Education | Education]]
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 DEAQ consisted of variables in the following subsections:​ DEAQ consisted of variables in the following subsections:​
  
-  * [[Depression (LIDAS)]] ​(depression- and anxiety-related questions)+  * [[Depression (LIDAS)]] ​-> note that for DEAQ, the original LIDAS was extended with various additional ​depression- and anxiety-related questions
   * [[Smoking & tobacco use]]    * [[Smoking & tobacco use]] 
   * [[Education | Education]]   * [[Education | Education]]
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 This project was funded by the Dutch research infrastructure for biobanking (BBMRI-NL) as Rainbow project Phenomics 2.0 – proof of principle for major depressive disorder (RP-12). ​ This project was funded by the Dutch research infrastructure for biobanking (BBMRI-NL) as Rainbow project Phenomics 2.0 – proof of principle for major depressive disorder (RP-12). ​
 +
 +==== Publications using DEPQ/DEAQ data ====
 +  * Vreijling et al. (2023) [[https://​www.sciencedirect.com/​science/​article/​pii/​S0165032722012514?​via%3Dihub|Sociodemographic,​ lifestyle and clinical characteristics of energy-related depression symptoms: A pooled analysis of 13,965 depressed cases in 8 Dutch cohorts]]. J Aff Dis 323: 1-9
 +  * Huider et al. (2024) [[https://​doi.org/​10.1017/​thg.2024.4|Genomics Research of Lifetime Depression in the Netherlands:​ The BIObanks Netherlands Internet Collaboration (BIONIC) Project]]. Twin Research and Human Genetics
  
bionic.1677164914.txt.gz · Last modified: 2025/02/05 14:49 (external edit)