food_allergy_definition
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food_allergy_definition [2022/07/01 15:40] laura [Calculation of food allergy definition] |
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| Researchers from the [[https://www.rug.nl/staff/j.m.vonk/|University Medical Center Groningen]] developed a definition of food allergy for all Lifelines participants (adults and children) using the [[allergies|allergy variables]] from [[2A]]. ([[sections]]: [[Diseases & symptoms]] ([[Allergies]]) and [[secondary & linked variables]]).\\ | Researchers from the [[https://www.rug.nl/staff/j.m.vonk/|University Medical Center Groningen]] developed a definition of food allergy for all Lifelines participants (adults and children) using the [[allergies|allergy variables]] from [[2A]]. ([[sections]]: [[Diseases & symptoms]] ([[Allergies]]) and [[secondary & linked variables]]).\\ | ||
| - | The Food allergy definition can be requested in the Lifelines catalogue or by mail (data@lifelines.nl).\\ | + | The Food allergy definition can be requested in the [[https://data-catalogue.lifelines.nl/|Lifelines catalogue]].\\ |
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| ===== Background ===== | ===== Background ===== | ||
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| ===== Calculation of food allergy definition ===== | ===== Calculation of food allergy definition ===== | ||
| The calculation of the food allergy definition consisted of three steps: 1) coding of open text variables, 2) defining and calculating criteria to define food allergy, and 3) creating the overall food allergy variables. | The calculation of the food allergy definition consisted of three steps: 1) coding of open text variables, 2) defining and calculating criteria to define food allergy, and 3) creating the overall food allergy variables. | ||
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| === 1. Coding of open text variables === | === 1. Coding of open text variables === | ||
| At the start of the process, the responses from participants on "other allergen", "other reaction", and "other person who diagnosed the food allergy" are coded. The allergens and reactions were coded as //common//, //less common//, and //uncommon// using the tables as descibed by [[https://doi.org/10.1371/journal.pone.0231818|Westerlaken-van Ginkel et al. (2020)]]. These original coding tables were slightly changed after reachging consensus. The "other person" items have been coded into //alternative practitioner//, //other person//, and //no person mentioned//. | At the start of the process, the responses from participants on "other allergen", "other reaction", and "other person who diagnosed the food allergy" are coded. The allergens and reactions were coded as //common//, //less common//, and //uncommon// using the tables as descibed by [[https://doi.org/10.1371/journal.pone.0231818|Westerlaken-van Ginkel et al. (2020)]]. These original coding tables were slightly changed after reachging consensus. The "other person" items have been coded into //alternative practitioner//, //other person//, and //no person mentioned//. | ||
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| === 2. Defining and calculating criteria to define food allergy === | === 2. Defining and calculating criteria to define food allergy === | ||
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| * **Criterium 4:** the duration of the symptoms is longer than 1 week | * **Criterium 4:** the duration of the symptoms is longer than 1 week | ||
| * **Criterium 5:** a negative double blind placebo controlled food provocation test | * **Criterium 5:** a negative double blind placebo controlled food provocation test | ||
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| === 3. Creating overall food allergy variables === | === 3. Creating overall food allergy variables === | ||
| Food allergy was coded as //no food allergy (0)//, //indeterminate food allergy (1)//, and //likely food allergy (2)// according to the flow diagram provided in the paper of [[https://doi.org/10.1371/journal.pone.0231818|Westerlaken-van Ginkel et al. (2020)]]. | Food allergy was coded as //no food allergy (0)//, //indeterminate food allergy (1)//, and //likely food allergy (2)// according to the flow diagram provided in the paper of [[https://doi.org/10.1371/journal.pone.0231818|Westerlaken-van Ginkel et al. (2020)]]. | ||
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| - A version without incorporating criterium 3 as there were many participants who reported a likely allergen and a likely reaction while the other four criteria were not unlikely. | - A version without incorporating criterium 3 as there were many participants who reported a likely allergen and a likely reaction while the other four criteria were not unlikely. | ||
| - A version including only criterium 1 and 2, to make the definition comparable to the one for children and adolescents. | - A version including only criterium 1 and 2, to make the definition comparable to the one for children and adolescents. | ||
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| === Remarks from the UMCG researchers === | === Remarks from the UMCG researchers === | ||
| - If a participant has two different questionnaires available, the quetsionnaire with the highest score on food allergy is selected. | - If a participant has two different questionnaires available, the quetsionnaire with the highest score on food allergy is selected. | ||
| - If a researcher wants to investigate food allergy in both children/adolescents and adults it is recommended to use //foodallergy_score_all_c_1//. If a researcher wants to investigate food allergy in adults only, it is recommended to use //foodallergy_score_adu_c_2// and use the //foodallergy_score_adu_c_3// variable in a sensitivity analysis. | - If a researcher wants to investigate food allergy in both children/adolescents and adults it is recommended to use //foodallergy_score_all_c_1//. If a researcher wants to investigate food allergy in adults only, it is recommended to use //foodallergy_score_adu_c_2// and use the //foodallergy_score_adu_c_3// variable in a sensitivity analysis. | ||
| - In the future the type of foods and the type of reactions will be classified and added. | - In the future the type of foods and the type of reactions will be classified and added. | ||
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| ===== Variables ===== | ===== Variables ===== | ||
food_allergy_definition.1656682849.txt.gz · Last modified: 2025/02/05 14:49 (external edit)
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