gwas
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gwas [2020/06/22 17:21] trynke |
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| GWAS is one of Lifelines' [[additional assessments]] and contains the genome-wide [[https://en.wikipedia.org/wiki/Single-nucleotide_polymorphism|SNP]] data of 15.400 adult Lifelines participants derived from the [[https://www.illumina.com/products/by-type/clinical-research-products/human-cytosnp-12.html|Illumina CytoSNP-12v2 array]].\\ | GWAS is one of Lifelines' [[additional assessments]] and contains the genome-wide [[https://en.wikipedia.org/wiki/Single-nucleotide_polymorphism|SNP]] data of 15.400 adult Lifelines participants derived from the [[https://www.illumina.com/products/by-type/clinical-research-products/human-cytosnp-12.html|Illumina CytoSNP-12v2 array]].\\ | ||
| - | The name GWAS might be confusing, as the assessment is not a [[https://en.wikipedia.org/wiki/Genome-wide_association_study|"genome wide association study"]] in itself, but rather the formation of a database of SNP data that can be used to perform such studies.\\ | + | The name GWAS might be confusing, as the assessment is not a [[https://en.wikipedia.org/wiki/Genome-wide_association_study|"genome wide association study"]] in itself, but rather the formation of a database of SNP data that can be used, together with Lifelines phenotype data, to perform such studies.\\ |
| Note that a second set of participants is genotyped in the [[UGLI]] project. | Note that a second set of participants is genotyped in the [[UGLI]] project. | ||
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| | Age category 18-64 | N=13890 | | | Age category 18-64 | N=13890 | | ||
| | Age category 65+ | N=1510 | | | Age category 65+ | N=1510 | | ||
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| + | {{:gwas_age_distribution.jpg?400|}} | ||
| ===== SNP array ===== | ===== SNP array ===== | ||
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