Differences

This shows you the differences between two versions of the page.

--- hscrp [2025/08/05 07:06] – petra_vinke
+++ hscrp [2025/12/08 12:58] (current) – [Table] simone
@@ Line 9: / Line 9: @@
 | hscrp_result_all_m_3  | CRPH           | CRPL3              | Roche (Modular)  | Heparin    | ~1k ([[1A]]) and ~0.5k ([[2A]])  |
-hscrp_result_all_m_2 and hscrp_result_all_m_3 only differ in the supplier. This does not have an effect on the measured values.\\
+hscrp_result_all_m_1 and hscrp_result_all_m_2 only differ in the tube type. This has not affected the measured values (externally validated in N=100 samples).
-hscrp_result_all_m_1 differs from hscrp_result_all_m_2 and hscrp_result_all_m_3 in the type of tube used to collect the sample. This causes differences in the measured values. hscrp_result_all_m_2/hscrp_result_all_m_3 values can be converted to hscrp_result_all_m_1 using the formula: SCRP = 0.92 x LCRP/CRPH - 0.01.
+hscrp_result_all_m_1 and hscrp_result_all_m_2 differ from hscrp_result_all_m_3 in the supplier of the assay. This causes differences in the measured values. hscrp_result_all_m_1 and hscrp_result_all_m_2 values can be adjusted to be similar to hscrp_result_all_m_3 using the formula: //adjusted variable = 0.92 x unadjusted - 0.01//, that is //hscrp_result_all_m_1_adjusted = 0.92 x hscrp_result_all_m_1 – 0.01// and //hscrp_result_all_m_2_adjusted = 0.92 x hscrp_result_all_m_2 – 0.01//.
+An adjusted variable was created by Lifelines Data Management, combining hscrp_result_all_m_1_adjusted, hscrp_result_all_m_2_adjusted and hscrp_result_all_m_3 into one variabele (hscrp_result_all_c_1) at 1A. This variable will soon be available through the Lifelines catalogue.
+^ Variable code         ^ Variable name          ^ Participants   ^
+| hscrp_result_all_c_1  |  hscrp_adjusted_total  | ~57k ([[1A]])  |
 **Please note:**
-- the use of the conversion formula above has led to some questions. The formula is currently (summer 2025) under review, updated instructions will follow as soon as possible.
-- 3A hscrp_result_all_m_1 data was mistakenly released until May 2025.
+- Until October 2025, this information was displayed wrongly on the wiki page. It was mistakenly mentioned that difference in supplier did not have an effect on measured values, while difference in tube type did have an effect. This is the other way around. A wrong formula was displayed (<del>//hscrp_result_all_m_1 = 0.92 x hscrp_result_all_m_2/3 – 0.01//</del>)
+- Until May 2025, in Assessment 3A, PLCR (platelet large cell ratio) data was mistakely released under the name hscrp_result_all_m_1. Note that the error only relates to 3A. The name was corrected to plcr_result_all_m_1.