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| pulmonary_function_test [2020/05/15 15:48] – trynke | pulmonary_function_test [2025/02/05 13:49] (current) – external edit 127.0.0.1 |
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| Spirometry ([[sections|section]]: [[physical state]]) is measured in [[start|Lifelines]] participants aged 8 years and older during: | Spirometry ([[sections|section]]: [[physical state]]) is measured in [[start|Lifelines]] participants aged 8 years and older during: |
| * [[1A Visit 1]] (in ~123.000 particpants, including ~10.000 [[children]]) | * [[1A Visit 1]] (in ~123.000 participants, including ~10.000 [[children]]) |
| * [[2A Visit 1]] (in ~32.000 adult participants that also underwent the test at baseline) | * [[2A Visit 1]] (in ~32.000 adult participants that also underwent the test at baseline) |
| * [[3A Visit 1]] | * [[3A Visit 1]] (in participants of 13 years and older) |
| | Besides the raw data, information on the [[spirometry_validation|validity of the spirometry and GLI reference values]] have been developed. |
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| ===== Device ===== | ===== Device ===== |
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| Spirometry was performed following ATS guidelines using a Welch Allyn Version 1.6.0.489, PC-based SpiroPerfect with CardioPerfect Workstation software. The Welch Allyn SpiroPerfect device ({{ :spiroperfect_manual.pdf |}}) consists of a pressure tubing (6.6 ft/2.0m), nose clip, disposable flow transducer and calibration syringe. | Spirometry was performed following ATS guidelines using a Welch Allyn Version 1.6.0.489, PC-based SpiroPerfect with CardioPerfect Workstation software. The Welch Allyn SpiroPerfect device ({{ :spiroperfect_manual.pdf |}}) consists of a pressure tubing (6.6 ft/2.0m), nose clip, disposable flow transducer and calibration syringe.\\ |
| | As of June 2021, MADA-83 bacteria filters are implemented in our Welch Allyn spirometry devices to prevent the spread of Covid-19. The measurement settings did not change.\\ |
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| ===== Variables ===== | ===== Variables ===== |
| ^ Variable ^ Meaning ^ | ^ Definition English ^ Definition Dutch ^ Code ^ Variable ^ Assessment ^ Age ^ |
| | FVC | FVC, highest value in L | | | do you have asthma? | heeft u astma? | spirometry_astma_all_q_1 | astma | [[1A Visit 1|1A]] [[2A Visit 1|2A]] | 8+/18+ | |
| | FEV1 | FEV1, highest value in L | | | do you have copd? | heeft u codp? | spirometry_copd_all_q_1 | copd | [[2A Visit 1|2A]] | 18+ | |
| | MAXFVCFEV1 | FVC + FEV1, highest value in L | | | do you smoke, or did you smoke in the past month? | rookt u nu, of heeft u de afgelopen maand nog gerookt? | spirometry_smoking_all_q_1 | spirosmk3 | [[1A Visit 1|1A]] [[2A Visit 1|2A]] | 8+/18+ | |
| | FEF25 | FEF25 of MAXFVCFEV1 in L/s | | | spirometry performed | longfunctie onderzocht | spirometry_performed_all_m_1/2 | longond_1 | [[1A Visit 1|1A]] [[2A Visit 1|2A]] | 8+/18+ | |
| | FEF25_75 | FEF25_75 of MAXFVCFEV1 in L/s | | | if not, reason: / spirometry performed | indien nee, reden: / longfunctie onderzocht | spirometry_performed_all_m_2_a | spiroreden | [[2A Visit 1|2A]] | 8+/18+ | |
| | FEF50 | FEF50 of MAXFVCFEV1 in L/s | | | number of attempts selected by research nurse for lung function assessment | aantal door doktersassistent geselecteerde pogingen voor de longfunctiemeting | spirometry_attempts_all_m_1 | number_of_attempts | [[3A Visit 1|3A]] | 13+ | |
| | FEF75 | FEF75 of MAXFVCFEV1 in L/s | | | fef25 of maxfvcfev1 (in liter/sec) | fef25 van maxfvcfev1 (liter/sec) | spirometry_fef25_all_m_1 | fef25 | [[1A Visit 1|1A]] [[2A Visit 1|2A]] [[3A Visit 1|3A]] | 8+/18+/13+ | |
| | PEF | PEF of MAXFVCFEV1 in L/s | | | fef25_75 of maxfvcfev1 (in liter/sec) | fef25_75 van maxfvcfev1 (liter/sec) | spirometry_fef2575_all_m_1 | fef25_75 | [[1A Visit 1|1A]] [[2A Visit 1|2A]] [[3A Visit 1|3A]] | 8+/18+/13+ | |
| | REVAFW_SPEC | Pulmonologist - Assessment | | | fef50 of maxfvcfev1 (in liter/sec) | fef50 van maxfvcfev1 (liter/sec) | spirometry_fef50_all_m_1 | fef50 | [[1A Visit 1|1A]] [[2A Visit 1|2A]] [[3A Visit 1|3A]] | 8+/18+/13+ | |
| | REVAFW1_AS | LFC Assistant - There are abnormalities to airway obstruction, FEV1/FVC <70% | | | fef75 of maxfvcfev1 (in liter/sec) | fef75 van maxfvcfev1 (liter/sec) | spirometry_fef75_all_m_1 | fef75 | [[1A Visit 1|1A]] [[2A Visit 1|2A]] [[3A Visit 1|3A]] | 8+/18+/13+ | |
| | REVAFW1_SPEC | Pulmonologist - There are abnormalities to airway obstruction, FEV1/FVC <70% | | | fev1 (highest value in liter) | fev1(hoogste waarde in liters) | spirometry_fev1_all_m_1 | fev1 | [[1A Visit 1|1A]] [[2A Visit 1|2A]] [[3A Visit 1|3A]] | 8+/18+/13+ | |
| | REVAFW2_AS | LFC Assistant - There is a reduced VC that is <80% predicted | | | fvc (highest value in liter) | fvc (hoogste waarde in liters) | spirometry_fvc_all_m_1 | fvc | [[1A Visit 1|1A]] [[2A Visit 1|2A]] [[3A Visit 1|3A]] | 8+/18+/13+ | |
| | REVAFW2_SPEC | Pulmonologist - There is a reduced VC that is <80% predicted | | | fvc + fev1 (highest value in liter) | fvc + fev1 (hoogste waarde) | spirometry_maxfvcfev1_all_m_1 | maxfvcfev1 | [[1A Visit 1|1A]] [[2A Visit 1|2A]] | 8+/18+ | |
| | REVAFW3_AS | LFC Assistant - There is a flow-volume curve with an abnormal gradient, namely… | | | pef of maxfvcfev1 (in liter/sec) | pef van maxfvcfev1 (in liter/sec) | spirometry_pef_all_m_1 | pef | [[1A Visit 1|1A]] [[2A Visit 1|2A]] | 8+/18+ | |
| | REVAFW3_SPEC | Pulmonologist - There is a flow-volume curve with an abnormal gradient, namely… | | | lung function assessment completed | beoordeling longfunctie afgerond | spirometry_reviewed_all_e_1 | check_final | [[1A Visit 1|1A]] [[2A Visit 1|2A]] | 8+/18+ | |
| | REVIEW_AS | LFC Assistant - Technical Assessment | | | lfc assistant - assessment performed | lfc assistent - beoordeling afgevinkt | spirometry_reviewed_all_e_1_a | check_as | [[1A Visit 1|1A]] [[2A Visit 1|2A]] | 8+/18+ | |
| | REVIEW_SPEC | Pulmonologist - Technical Assessment | | | pulmonologist - assessment performed | longarts - beoordeling afgevinkt | spirometry_reviewed_all_e_1_b | check_spec | [[1A Visit 1|1A]] [[2A Visit 1|2A]] | 8+/18+ | |
| | CHECK_AS | Review signed off | | | lfc assistant - technical assessment | lfc assistent - technische beoordeling | spirometry_technicalquality_all_e_1_a | review_as | [[1A Visit 1|1A]] [[2A Visit 1|2A]] | 8+/18+ | |
| | CHECK_FINAL | Lung function assessment completed | | | pulmonologist - technical assessment | longarts - technische beoordeling | spirometry_technicalquality_all_e_1_b | review_spec | [[1A Visit 1|1A]] [[2A Visit 1|2A]] | 8+/18+ | |
| | | lung function assessment of sufficient quality | longfunctiemeting van voldoende kwaliteit | spirometry_qualitycontrol_all_qc_1 | qc_jv | [[3A Visit 1|3A]] | 13+ | |
| | | research nurse - technical review | doktersassistent - technische beoordeling | spirometry_technicalquality_all_e_2 | technische_kwaliteit | [[3A Visit 1|3A]] | 13+ | |
| | | lfc technician - technical review | longfunctieanalist - technische beoordeling | spirometry_technicalquality_all_e_2_a | spiro_functieanalist_spiro_conclusion | [[3A Visit 1|3A]] | 13+ | |
| | | research nurse - lung fuction result needs to be reviewed by lfc assistant | doktersassistent - resultaat longfunctie moet worden beoordeeld door longfunctieanalist | spirometry_toreview_all_e_1 | needs_review | [[3A Visit 1|3A]] | 13+ | |
| | | lfc assistant - assessment | lfc assistent beoordeling | spirometry_conclusion_all_e_1_a | revafw_as | [[1A Visit 1|1A]] [[2A Visit 1|2A]] | 8+/18+ | |
| | | pulmonologist - assessment | longarts - beoordeling | spirometry_conclusion_all_e_1_b | revafw_spec | [[1A Visit 1|1A]] [[2A Visit 1|2A]] | 8+/18+ | |
| | | lfc assistant - there are abnormalities to airway obstruction, fev1/fvc <70% | lfc assistent - er zijn afwijkingen voor luchtwegobstructie, fev1/fvc < 70% | spirometry_obstruction_all_e_1_a | revafw1_as | [[1A Visit 1|1A]] | 8+ | |
| | | pulmonologist - there are abnormalities to airway obstruction, fev1/fvc <70% | longarts - er zijn afwijkingen voor luchtwegobstructie, fev1/fvc < 70% | spirometry_obstruction_all_e_1_b | revafw1_spec | [[1A Visit 1|1A]] | 8+ | |
| | | lfc assistant - there are abnormalities to airway obstruction, fev1/fvc <75% | lfc assistent - er zijn afwijkingen voor luchtwegobstructie, fev1/fvc < 75% | spirometry_obstruction_all_e_2_a | revafw1_kp_as | [[1A Visit 1|1A]] [[2A Visit 1|2A]] | 8+/18+ | |
| | | pulmonologist - there are abnormalities to airway obstruction, fev1/fvc <75% | longarts - er zijn afwijkingen voor luchtwegobstructie, fev1/fvc < 75% | spirometry_obstruction_all_e_2_b | revafw1_kp_spec | [[1A Visit 1|1A]] [[2A Visit 1|2A]] | 8+/18+ | |
| | | lfc assistant - there is a flow-volume curve with an abnormal gradient, namely | lfc assistent - er is sprake van een flow-volume curve met een abnormaal verloop nl | spirometry_abnormalcurve_all_e_1_a | revafw3_as | [[1A Visit 1|1A]] [[2A Visit 1|2A]] | 8+/18+ | |
| | | pulmonologist - there is a flow-volume curve with an abnormal gradient, namely | longarts - er is sprake van een flow-volume curve met een abnormaal verloop nl | spirometry_abnormalcurve_all_e_1_b | revafw3_spec | [[1A Visit 1|1A]] [[2A Visit 1|2A]] | 8+/18+ | |
| | | lfc assistant - there is a reduced vc that is <80% predicted | lfc assistent - er is sprake van een verlaagde vc die < 80% predicted | spirometry_reducedvc_all_e_1_a | revafw2_as | [[1A Visit 1|1A]] [[2A Visit 1|2A]] | 8+/18+ | |
| | | pulmonologist - there is a reduced vc that is <80% predicted | longarts - er is sprake van een verlaagde vc die < 80% predicted | spirometry_reducedvc_all_e_1_b | revafw2_spec | [[1A Visit 1|1A]] [[2A Visit 1|2A]] | 8+/18+ | |
| | | lfc assistant - remark | lfc assistant - opmerking | spirometry_remarks_all_e_1_a | remark_as | [[1A Visit 1|1A]] [[2A Visit 1|2A]] | 8+/18+ | |
| | | pulmonologist - remark | longarts - opmerking | spirometry_remarks_all_e_1_b | remark_spec | [[1A Visit 1|1A]] [[2A Visit 1|2A]] | 8+/18+ | |
