High-sensitivity CRP (hsCRP) levels in Lifelines participants were determined in blood samples (section: Physical state) using three different lab-methods.
The difference between the three methods are stated in the table.

hscrp_result_all_m_1 and hscrp_result_all_m_2 only differ in the tube type. This has not affected the measured values (externally validated in N=100 samples). hscrp_result_all_m_1 and hscrp_result_all_m_2 differ from hscrp_result_all_m_3 in the supplier of the assay. This causes differences in the measured values. hscrp_result_all_m_1 and hscrp_result_all_m_2 values can be converted to hscrp_result_all_m_3 using the formula: adjusted variable = 0.92 x unadjusted - 0.01, that is hscrp_result_all_m_3 = 0.92 x hscrp_result_all_m_1 – 0.01 and hscrp_result_all_m_3 = 0.92 x hscrp_result_all_m_2 – 0.01.

Please note:

- Until October 2025, this formula was displayed wrong on this wiki page. It mistakenly mentioned that difference in supplier did not have an effect on measured values, while difference in tube type did have an effect. This is the other way around. A wrong formula was displayed (hscrp_result_all_m_1 = 0.92 x hscrp_result_all_m_2/3 – 0.01)

- 3A hscrp_result_all_m_1 data was mistakenly released until May 2025.