Lifelines assesses health in participants, but also collects information about their family history of diseases.
In many cases, these family members are also Lifelines participants. This knowledge allows for a close examination of diseases that do or do not run in families.

The following subsections fall under the section Family health:

1. Family deaths
2. Familial cancer
3. Familial cardiovascular disease
4. Familial chronic fatigue syndrome
5. Familial diabetes
6. Familial digestive diseases
7. Familial kidney diseases
8. Familial mental illness
9. Familial musculoskeletal diseases
10. Familial neurological diseases
11. Familial respiratory diseases
12. Familial diseases (other)